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GBP1 Monoclonal antibody, PBS Only

GBP1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, rat, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A10E8

Cat no : 67161-1-PBS

Print datasheet

Synonyms

Guanine nucleotide-binding protein 1, GTP-binding protein 1, GBP-1, GBP 1, EC:3.6.1.-

验证数据展示

  • WB analysis of HeLa using 67161-1-Ig (same clone as 67161-1-PBS)

    WB analysis of HeLa using 67161-1-Ig (same clone as 67161-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67161-1-Ig (GBP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67161-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67161-1-Ig (GBP1 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67161-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GBP1 antibody included
  • IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67161-1-Ig (GBP1 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67161-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GBP1 antibody included
Planning an IHC experiment? We recommend our IHCeasy GBP1 Ready-To-Use IHC Kit. GBP1 primary antibody included.

产品信息

67161-1-PBS targets GBP1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat, pig samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, rat, pig
Immunogen GBP1 fusion protein Ag7767 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name GTP binding protein 1
Synonyms Guanine nucleotide-binding protein 1, GTP-binding protein 1, GBP-1, GBP 1, EC:3.6.1.-
Calculated Molecular Weight 68 kDa
Observed Molecular Weight 68 kDa
GenBank Accession NumberBC002666
Gene Symbol GBP1
Gene ID (NCBI) 2633
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP32455
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Guanylate binding protein 1 (GBP1) belongs to the dynamin superfamily of large GTPases. The expression of GBP1 is induced by IFN and GBP1 is characterized by its ability to specifically bind guanine nucleotides such as GMP, GDP, and GTP and its ability to hydrolyze GTP to GDP and GMP. GBP1 is induced in response to type I and type II IFNs and as such plays a role in protective immunity against a spectrum of intracellular pathogens ranging from viruses to bacteria to protozoa, such as negative-strand RNA Rhabdovirus, vesicular stomatitis virus and the positive-strand RNA Picornovirus, encephalomyocarditis virus in cultured cells, the inhibition of Chlamydia trachomatis, Toxoplasma gondii, and Salmonella enterica.