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验证数据展示

  • WB analysis of HeLa using 67161-1-Ig (same clone as 67161-1-PBS)

    WB analysis of HeLa using 67161-1-Ig (same clone as 67161-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67161-1-Ig (GBP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67161-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67161-1-Ig (GBP1 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67161-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GBP1 antibody included
  • IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    IHC staining of human ovary tumor using 67161-1-Ig (same clone as 67161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 67161-1-Ig (GBP1 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67161-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GBP1 antibody included

GBP1 Monoclonal antibody, PBS Only

GBP1 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67161-1-PBS

产品说明书

CloneNo. 2A10E8

宿主/亚型

Mouse / IgG2b

种属反应性

human, rat, pig

应用

WB, IHC, Indirect ELISA

别名

Guanine nucleotide-binding protein 1, GTP-binding protein 1, GBP-1, GBP 1, EC:3.6.1.-

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy GBP1 Ready-To-Use IHC Kit. GBP1 primary antibody included.

产品信息

67161-1-PBS targets GBP1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat, pig samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, rat, pig
免疫原 GBP1 fusion protein Ag7767 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 GTP binding protein 1
别名 Guanine nucleotide-binding protein 1, GTP-binding protein 1, GBP-1, GBP 1, EC:3.6.1.-
计算分子量 68 kDa
观测分子量 68 kDa
GenBank蛋白编号BC002666
基因名称 GBP1
Gene ID (NCBI) 2633
RRIDAB_2882457
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP32455
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Guanylate binding protein 1 (GBP1) belongs to the dynamin superfamily of large GTPases. The expression of GBP1 is induced by IFN and GBP1 is characterized by its ability to specifically bind guanine nucleotides such as GMP, GDP, and GTP and its ability to hydrolyze GTP to GDP and GMP. GBP1 is induced in response to type I and type II IFNs and as such plays a role in protective immunity against a spectrum of intracellular pathogens ranging from viruses to bacteria to protozoa, such as negative-strand RNA Rhabdovirus, vesicular stomatitis virus and the positive-strand RNA Picornovirus, encephalomyocarditis virus in cultured cells, the inhibition of Chlamydia trachomatis, Toxoplasma gondii, and Salmonella enterica.