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Species Reactivity
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GCGR Recombinant antibody, PBS Only

GCGR Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241501C4

Cat no : 84237-5-PBS

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Synonyms

验证数据展示

  • WB analysis using 84237-5-RR (same clone as 84237-5-PBS)

    WB analysis using 84237-5-RR (same clone as 84237-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84237-5-RR (GCGR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84237-5-PBS in a different storage buffer formulation.

产品信息

84237-5-PBS targets GCGR in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen GCGR fusion protein Ag24861 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name glucagon receptor
Synonyms
Calculated Molecular Weight 477 aa, 54 kDa
Observed Molecular Weight62-68 kDa
GenBank Accession NumberBC104854
Gene Symbol GCGR
Gene ID (NCBI) 2642
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP47871
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Glucagon receptor (GCGR) is a secretin-like (class B) family of G-protein coupled receptors (GPCRs). It plays an important role in elevating the glucose concentration in the blood and has thus become one of the promising therapeutic targets for treating type 2 diabetes mellitus (PMID: 26236379). GCGR is a 62-kDa glycoprotein that contains at least four N-linked oligosaccharide chains (PMID: 2174441; 15245877). Defects in the gene of GCGR cause non-insulin-dependent diabetes mellitus (NIDDM).