GDAP1L1 Monoclonal antibody, PBS Only

GDAP1L1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, mouse, rat, pig, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C7A3

Cat no : 68340-1-PBS

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Synonyms

dJ881L22.1, dJ995J12.1.1, DKFZp761K228, GDAP1 L1, GDAP1L1



产品信息

68340-1-PBS targets GDAP1L1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, pig, rabbit
Immunogen GDAP1L1 fusion protein Ag27717 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name ganglioside-induced differentiation-associated protein 1-like 1
Synonyms dJ881L22.1, dJ995J12.1.1, DKFZp761K228, GDAP1 L1, GDAP1L1
Calculated Molecular Weight 367 aa, 42 kDa
Observed Molecular Weight 38-40 kDa
GenBank Accession NumberBC009014
Gene Symbol GDAP1L1
Gene ID (NCBI) 78997
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96MZ0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) belongs to GST superfamily. Owing to its central role in mitochondrial fission, GDAP1L1 is a homologue of GDAP1 implicated in cellular processes, such as cell death, autophagy, aging, and immune response regulation (PMID:32230997). GDAP1L1, a fission factor controlling mitochondrial fission, induces fission upon translocation from the cytosol to mitochondria in response to stress condition (PMID:34638757). Furthermore, the activity of GDAP1L1 is dependent on Drp1. GDAP1, a paralog of GDAP1L1, evokes mitochondrial fragmentation only in the presence of Drp1 in HeLa cells (PMID:19782751).