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验证数据展示

  • WB analysis using 68768-1-Ig (same clone as 68768-1-PBS)

    WB analysis using 68768-1-Ig (same clone as 68768-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68768-1-Ig (GDF15 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68768-1-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP50133-1

    Sandwich ELISA standard curve of MP50133-1

    Sandwich ELISA standard curve of MP50133-1, GDF15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-3-PBS. Detection antibody: HRP-conjugated 68768-1-PBS. Standard:Ag33750. Range: 1.563-100 ng/mL.

  • Sandwich ELISA standard curve of MP50133-2

    Sandwich ELISA standard curve of MP50133-2

    Sandwich ELISA standard curve of MP50133-2, GDF15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-4-PBS. Detection antibody: HRP-conjugated 68768-1-PBS. Standard:Ag33750. Range: 1.563-100 ng/mL.

  • Sandwich ELISA standard curve of MP50133-4

    Sandwich ELISA standard curve of MP50133-4

    Sandwich ELISA standard curve of MP50133-4, GDF15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-7-PBS. Detection antibody: HRP-conjugated 68768-1-PBS. Standard:Ag33750. Range: 1.563-100 ng/mL.

  • Sandwich ELISA standard curve of MP50133-5

    Sandwich ELISA standard curve of MP50133-5

    Sandwich ELISA standard curve of MP50133-5, GDF15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-1-PBS. Detection antibody: HRP-conjugated 68768-2-PBS. Standard:Ag33750. Range: 1.563-100 ng/mL.

  • Sandwich ELISA standard curve of MP50133-8

    Sandwich ELISA standard curve of MP50133-8

    Sandwich ELISA standard curve of MP50133-8, GDF15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-5-PBS. Detection antibody: HRP-conjugated 68768-1-PBS. Standard:Ag33750. Range: 1.563-100 ng/mL.

  • Sandwich ELISA standard curve of MP50133-9

    Sandwich ELISA standard curve of MP50133-9

    Sandwich ELISA standard curve of MP50133-9, GDF15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-6-PBS. Detection antibody: HRP-conjugated 68768-1-PBS. Standard:Ag33750. Range: 1.563-100 ng/mL.

  • Sample test of MP50133-1

    Sample test of MP50133-1

    Cytometric bead array of cell line supernatant using MP50133-1, GDF-15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-3-PBS. Detection antibody: 68768-1-PBS. Supernatant (50μL/well) from the following cell lines were assayed: HepG2, LnCap, HT-1080. Complete culture medium was served as blank control.

  • Sample test of MP50133-2

    Sample test of MP50133-2

    Cytometric bead array of cell line supernatant using MP50133-2, GDF-15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-4-PBS. Detection antibody: 68768-1-PBS. Supernatant (50μL/well) from the following cell lines were assayed: HepG2, LnCap, HT-1080. Complete culture medium was served as blank control.

  • Sample test of MP50133-4

    Sample test of MP50133-4

    Cytometric bead array of cell line supernatant using MP50133-4, GDF-15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-7-PBS. Detection antibody: 68768-1-PBS. Supernatant (50μL/well) from the following cell lines were assayed: LnCap, HT-1080. Complete culture medium was served as blank control.

  • Sample test of MP50133-5

    Sample test of MP50133-5

    Cytometric bead array of cell line supernatant using MP50133-5, GDF-15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-1-PBS. Detection antibody: 68768-2-PBS. Supernatant (50μL/well) from the following cell lines were assayed: LnCap, HT-1080. Complete culture medium was served as blank control.

  • Sample test of MP50133-8

    Sample test of MP50133-8

    Cytometric bead array of LnCap cells supernatant using MP50133-8, GDF-15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-5-PBS. Detection antibody: 68768-1-PBS. Complete culture medium was served as blank control.

  • Sample test of MP50133-9

    Sample test of MP50133-9

    Cytometric bead array of cell line supernatant using MP50133-9, GDF-15 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68768-6-PBS. Detection antibody: 68768-1-PBS. Supernatant (50μL/well) from the following cell lines were assayed: LnCap, HT-1080. Complete culture medium was served as blank control.

  • IF Staining of HeLa using 68768-1-Ig (same clone as 68768-1-PBS)

    IF Staining of HeLa using 68768-1-Ig (same clone as 68768-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using GDF15 antibody (68768-1-Ig, Clone: 1B1H4 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68768-1-PBS in a different storage buffer formulation.

GDF-15 Monoclonal antibody, PBS Only (Capture/Detector)

GDF-15 Monoclonal Antibody for WB, IF/ICC, Sandwich ELISA, Indirect ELISA, Sample test
Cat No. 68768-1-PBS

产品说明书

CloneNo. 1B1H4

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IF/ICC, Sandwich ELISA, Indirect ELISA, Sample test

别名

GDF15, 1B1H4, GDF 15, growth differentiation factor 15, Growth/differentiation factor 15

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68768-1-PBS targets GDF-15 as part of a matched antibody pair:

MP50133-1: 68768-3-PBS capture and 68768-1-PBS detection (validated in Sandwich ELISA)

MP50133-2: 68768-4-PBS capture and 68768-1-PBS detection (validated in Sandwich ELISA)

MP50133-4: 68768-7-PBS capture and 68768-1-PBS detection (validated in Sandwich ELISA)

MP50133-5: 68768-1-PBS capture and 68768-2-PBS detection (validated in Sandwich ELISA)

MP50133-8: 68768-5-PBS capture and 68768-1-PBS detection (validated in Sandwich ELISA)

MP50133-9: 68768-6-PBS capture and 68768-1-PBS detection (validated in Sandwich ELISA)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, IF/ICC, Sandwich ELISA, Indirect ELISA, Sample test Application Description
经测试反应性 human
免疫原 GDF-15 fusion protein Ag33750 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 growth differentiation factor 15
别名 GDF15, 1B1H4, GDF 15, growth differentiation factor 15, Growth/differentiation factor 15
计算分子量 34 kDa
观测分子量34 kDa
GenBank蛋白编号BC008962
基因名称 GDF15
Gene ID (NCBI) 9518
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ99988
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Growth differentiation factor 15 (GDF15), also known as macrophage inhibitory cytokine-1 (MIC-1), is a protein of the transforming growth factor beta (TGFb) superfamily that regulates inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is a stress-induced cytokine and associated with hypoxia, inflammation and oxidative stress, it is also released from endothelial cells after stimulation with pro-inflammatory cytokines. GDF15 has been suggested as a target and biomarker for cardiovascular disease as it plays a cardioprotective role in the adult heart. GDF15 is highly expressed in the placenta. GDF15 is known to be involved in human embryo development and necessary for the maintenance of pregnancy. GDF15 is also produced by adipocytes in response to oxidative stress, a well-known factor associated with preeclampsia.