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GIMAP5 Monoclonal antibody, PBS Only

GIMAP5 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1B6F2

Cat no : 66943-1-PBS

Print datasheet

Synonyms

FLJ11296, GIMAP5, GTPase IMAP family member 5, GTPase, IMAP family member 5, hIAN5, HIMAP3, IAN 5, IAN4, IAN4L1, IAN5, IMAP3, Immunity associated protein 3

验证数据展示

  • WB analysis of Jurkat using 66943-1-Ig (same clone as 66943-1-PBS)

    WB analysis of Jurkat using 66943-1-Ig (same clone as 66943-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66943-1-Ig (GIMAP5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

产品信息

66943-1-PBS targets GIMAP5 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen GIMAP5 fusion protein Ag18045 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name GTPase, IMAP family member 5
Synonyms FLJ11296, GIMAP5, GTPase IMAP family member 5, GTPase, IMAP family member 5, hIAN5, HIMAP3, IAN 5, IAN4, IAN4L1, IAN5, IMAP3, Immunity associated protein 3
Calculated Molecular Weight 35 kDa
Observed Molecular Weight 30-35 kDa
GenBank Accession NumberBC011732
Gene Symbol GIMAP5
Gene ID (NCBI) 55340
RRIDAB_2882267
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96F15
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GIMAP5 gene encodes immunity-associated nucleotide 5 protein (IAN5) belonging to GTPase immune-associated protein subfamily. GIMAP5 is widely expressed with high levels in lymph node and spleen. The loss of Gimap5 (GTPase of the 5) gene function is the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding (BB) rat. Mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT-cell development, hematopoietic progenitor cell survival and the maintenance of normal liver function. GIMAP5 may regulate T lymphocyte survival by mechanisms that operate upstream of mitochondria.