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Host
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验证数据展示

  • WB analysis of Jurkat using 66943-1-Ig (same clone as 66943-1-PBS)

    WB analysis of Jurkat using 66943-1-Ig (same clone as 66943-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66943-1-Ig (GIMAP5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    IHC staining of human lymphoma using 66943-1-Ig (same clone as 66943-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 66943-1-Ig (GIMAP5 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66943-1-PBS in a different storage buffer formulation.

GIMAP5 Monoclonal antibody, PBS Only

GIMAP5 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66943-1-PBS

产品说明书

CloneNo. 1B6F2

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IHC, Indirect ELISA

别名

FLJ11296, GIMAP5, GTPase IMAP family member 5, GTPase, IMAP family member 5, hIAN5, HIMAP3, IAN 5, IAN4, IAN4L1, IAN5, IMAP3, Immunity associated protein 3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66943-1-PBS targets GIMAP5 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 GIMAP5 fusion protein Ag18045 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 GTPase, IMAP family member 5
别名 FLJ11296, GIMAP5, GTPase IMAP family member 5, GTPase, IMAP family member 5, hIAN5, HIMAP3, IAN 5, IAN4, IAN4L1, IAN5, IMAP3, Immunity associated protein 3
计算分子量 35 kDa
观测分子量 30-35 kDa
GenBank蛋白编号BC011732
基因名称 GIMAP5
Gene ID (NCBI) 55340
RRIDAB_2882267
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ96F15
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GIMAP5 gene encodes immunity-associated nucleotide 5 protein (IAN5) belonging to GTPase immune-associated protein subfamily. GIMAP5 is widely expressed with high levels in lymph node and spleen. The loss of Gimap5 (GTPase of the 5) gene function is the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding (BB) rat. Mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT-cell development, hematopoietic progenitor cell survival and the maintenance of normal liver function. GIMAP5 may regulate T lymphocyte survival by mechanisms that operate upstream of mitochondria.