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验证数据展示

  • WB analysis using 11254-1-AP (same clone as 11254-1-PBS)

    WB analysis using 11254-1-AP (same clone as 11254-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11254-1-AP (GLRX3 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach cancer using 11254-1-AP (same clone as 11254-1-PBS)

    IHC staining of human stomach cancer using 11254-1-AP (same clone as 11254-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11254-1-AP (GLRX3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

GLRX3 Polyclonal antibody, PBS Only

GLRX3 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11254-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

11254-1-PBS targets GLRX3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 GLRX3 fusion protein Ag1775 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutaredoxin 3
别名
计算分子量 37 kDa
观测分子量 37-40 kDa
GenBank蛋白编号BC014372
基因名称 GLRX3
Gene ID (NCBI) 10539
RRIDAB_2110374
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO76003
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals(PMID:20226171). Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially(PMID:19797004).