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  • Featured Product
  • KD/KO Validated

GLRX3 Polyclonal antibody, PBS Only

GLRX3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11254-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 11254-1-AP (same clone as 11254-1-PBS)

    WB analysis using 11254-1-AP (same clone as 11254-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11254-1-AP (GLRX3 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach cancer using 11254-1-AP (same clone as 11254-1-PBS)

    IHC staining of human stomach cancer using 11254-1-AP (same clone as 11254-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11254-1-AP (GLRX3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11254-1-PBS in a different storage buffer formulation.

产品信息

11254-1-PBS targets GLRX3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen GLRX3 fusion protein Ag1775 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name glutaredoxin 3
Synonyms
Calculated Molecular Weight 37 kDa
Observed Molecular Weight 37-40 kDa
GenBank Accession NumberBC014372
Gene Symbol GLRX3
Gene ID (NCBI) 10539
RRIDAB_2110374
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO76003
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals(PMID:20226171). Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially(PMID:19797004).