验证数据展示
产品信息
68156-1-PBS targets GNAI3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | Human, Mouse, Rat |
Immunogen | GNAI3 fusion protein Ag32662 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
Synonyms | 87U6, FLJ26559, G(i) alpha 3, GNAI3 |
Calculated Molecular Weight | 40 kDa |
Observed Molecular Weight | ~40 kDa |
GenBank Accession Number | BC025285 |
Gene Symbol | GNAI3 |
Gene ID (NCBI) | 2773 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P08754 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GNAI3 is a member of the Gi group proteins, which belong to the Gα protein family. GNAI3 is involved in several critical biological processes and regulates many cellular activities, including proliferation, differentiation, apoptosis, and migration. For example, GNAI3 can regulate a class of K+ channels in response to hormone and neurotransmitter signals. In addition to its function as a downstream signal pathway switch for receptors on the plasma membrane, GNAI3 has also been shown to localize to the centrosome and affect cytokinesis. These indicate that GNAI3 has important receptor-independent functions. The molecular weight of GNAI3 is 40 kDa. (PMID: 25444921, 34803495)