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GNB1L Polyclonal antibody

GNB1L Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 26484-1-AP

Print datasheet

Synonyms

DGCRK3, FKSG1, GNB1L, GY2, KIAA1645, WDR14, WDVCF

验证数据展示

  • WB analysis using 26484-1-AP

    WB analysis using 26484-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 26484-1-AP (GNB1L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA549 cells, Jurkat cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26484-1-AP targets GNB1L in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen GNB1L fusion protein Ag24391 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Synonyms DGCRK3, FKSG1, GNB1L, GY2, KIAA1645, WDR14, WDVCF
Calculated Molecular Weight 327 aa, 36 kDa
Observed Molecular Weight36 kDa, 18 kDa
GenBank Accession NumberBC012060
Gene Symbol GNB1L
Gene ID (NCBI) 54584
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9BYB4
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GNB1L (G-protein subunit beta 1 like), located at 22q11.2, encodes a G-protein L-subunit-like polypeptide which is a member of the WD repeat protein family (PMID: 20538345). In humans, the hemizygous deletion of GNB1L can cause sensorimotor gating defects, which are related to schizophrenia and other serious mental diseases (PMID: 32847500). Moreover, GNB1L is a key regulator of DDR signaling via its role as a co-chaperone specifically regulating PIKK proteins (PMID: 37541219). GNB1L has 2 isoforms 36 kDa and 22 kDa, about 22 kDa which may be produced by Alternative splicing.

实验方案

Product Specific Protocols
WB protocol for GNB1L antibody 26484-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols