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GNE Monoclonal antibody, PBS Only

GNE Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A11E10

Cat no : 67649-1-PBS

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Synonyms

DMRV, GLCNE, GNE, IBM2, ManAc kinase, NM, Uae1, UDP GlcNAc 2 epimerase

验证数据展示

  • WB analysis using 67649-1-Ig (same clone as 67649-1-PBS)

    WB analysis using 67649-1-Ig (same clone as 67649-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67649-1-Ig (GNE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67649-1-PBS in a different storage buffer formulation.

产品信息

67649-1-PBS targets GNE in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, rat
Immunogen GNE fusion protein Ag18702 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Synonyms DMRV, GLCNE, GNE, IBM2, ManAc kinase, NM, Uae1, UDP GlcNAc 2 epimerase
Calculated Molecular Weight 722 aa, 79 kDa
Observed Molecular Weight 79 kDa
GenBank Accession NumberBC121179
Gene Symbol GNE
Gene ID (NCBI) 10020
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y223
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.