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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 67649-1-Ig (same clone as 67649-1-PBS)

    WB analysis using 67649-1-Ig (same clone as 67649-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67649-1-Ig (GNE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67649-1-PBS in a different storage buffer formulation.

GNE Monoclonal antibody, PBS Only

GNE Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67649-1-PBS

产品说明书

CloneNo. 2A11E10

宿主/亚型

Mouse / IgG1

种属反应性

Human, rat

应用

WB, Indirect ELISA

别名

DMRV, GLCNE, GNE, IBM2, ManAc kinase, NM, Uae1, UDP GlcNAc 2 epimerase

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67649-1-PBS targets GNE in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, rat
免疫原 GNE fusion protein Ag18702 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
别名 DMRV, GLCNE, GNE, IBM2, ManAc kinase, NM, Uae1, UDP GlcNAc 2 epimerase
计算分子量 722 aa, 79 kDa
观测分子量 79 kDa
GenBank蛋白编号BC121179
基因名称 GNE
Gene ID (NCBI) 10020
RRIDAB_2882849
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9Y223
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.