验证数据展示
产品信息
10190-2-PBS targets GNL2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | GNL2 fusion protein Ag0243 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | guanine nucleotide binding protein-like 2 (nucleolar) |
别名 | |
计算分子量 | 731 aa, 84 kDa |
观测分子量 | 100 kDa |
GenBank蛋白编号 | BC000107 |
基因名称 | GNL2 |
Gene ID (NCBI) | 29889 |
RRID | AB_2110075 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q13823 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GNL2 ( G protein nucleolar 2) has a crucial role in the pathogenesis of gliomas by influencing key cellular processes, particularly enhanced protein synthesis, which ultimately contributes to the development of gliomas. In addition, GNL2 was found to affect the overall protein synthesis of ribosomal protein L11 in glioma cells. The calculated MW of GNL2 is 84 kDa, but the observed MW is around 100 kDa, which may be due to glycosylation modification.