验证数据展示
产品信息
67294-1-PBS targets GNMT in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Pig, Rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Pig, Rat |
免疫原 | GNMT fusion protein Ag4598 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | glycine N-methyltransferase |
别名 | glycine N methyltransferase, GNMT |
计算分子量 | 295 aa, 33 kDa |
观测分子量 | 33 kDa |
GenBank蛋白编号 | BC032627 |
基因名称 | GNMT |
Gene ID (NCBI) | 27232 |
RRID | AB_2882559 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q14749 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Glycine N-methyltransferase (GNMT, EC 2.1.1.20) was found originally as an enzyme regulating the ratio of SAM to S-adenosyl- homocysteine. GNMT is conservative among different animal species. Glycine-N methyltransferase (GNMT) is a potential tumor suppressor that is commonly inactivated in human hepatoma. GNMT is abundant in liver, but very low in HepG2 cells (PMID: 12566990).