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GPR126 Recombinant antibody, PBS Only

GPR126 Uni-rAbTM Recombinant Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

6M2

Cat no : 81632-1-PBS

Print datasheet

Synonyms

APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR

验证数据展示

  • IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

产品信息

81632-1-PBS targets GPR126 in IHC, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity Human, mouse
Immunogen GPR126 fusion protein Ag12195 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name G protein-coupled receptor 126
Synonyms APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR
Calculated Molecular Weight 1222 aa, 137 kDa
GenBank Accession NumberBC075798
Gene Symbol GPR126
Gene ID (NCBI) 57211
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ86SQ4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.