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  • Featured Product
  • KD/KO Validated

GPR137 Polyclonal antibody, PBS Only

GPR137 Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11929-1-PBS

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Synonyms

验证数据展示

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

产品信息

11929-1-PBS targets GPR137 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen GPR137 fusion protein Ag2611 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name G protein-coupled receptor 137
Synonyms
Calculated Molecular Weight 396 aa, 44 kDa
GenBank Accession NumberBC033920
Gene Symbol GPR137
Gene ID (NCBI) 56834
RRIDAB_10694423
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96N19
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

G protein-coupled receptors (GPRs) are highly related to oncogenesis and cancer metastasis. G protein-coupled receptor 137 (GPR137) was initially reported as a novel orphan GPR about 10 years ago. GPR137 is ubiquitously expressed in the central nervous system (CNS), mainly in the hippocampus (PMID: 22025619). GPR137 is involved in the progression of human glioma, suggesting GPR137 as a potential oncogene of glioma cells (PMID: 24870220). Recent study shows that GPR137 plays an important role in colon cancer cell proliferation (PMID: 25301753).