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验证数据展示

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

GPR137 Polyclonal antibody, PBS Only

GPR137 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 11929-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

11929-1-PBS targets GPR137 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 GPR137 fusion protein Ag2611 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 137
别名
计算分子量 396 aa, 44 kDa
GenBank蛋白编号BC033920
基因名称 GPR137
Gene ID (NCBI) 56834
RRIDAB_10694423
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96N19
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

G protein-coupled receptors (GPRs) are highly related to oncogenesis and cancer metastasis. G protein-coupled receptor 137 (GPR137) was initially reported as a novel orphan GPR about 10 years ago. GPR137 is ubiquitously expressed in the central nervous system (CNS), mainly in the hippocampus (PMID: 22025619). GPR137 is involved in the progression of human glioma, suggesting GPR137 as a potential oncogene of glioma cells (PMID: 24870220). Recent study shows that GPR137 plays an important role in colon cancer cell proliferation (PMID: 25301753).