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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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验证数据展示

  • IHC staining of mouse cerebellum using 13416-1-AP (same clone as 13416-1-PBS)

    IHC staining of mouse cerebellum using 13416-1-AP (same clone as 13416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 13416-1-AP (GPR17 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13416-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse cerebellum using 13416-1-AP (same clone as 13416-1-PBS)

    IF Staining of mouse cerebellum using 13416-1-AP (same clone as 13416-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse cerebellum tissue using GPR17 antibody (13416-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13416-1-PBS in a different storage buffer formulation.

GPR17 Polyclonal antibody, PBS Only

GPR17 Polyclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 13416-1-PBS

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF-P, Indirect ELISA

Synonyms

UDP/CysLT receptor, R12, P2Y-like receptor, P2Y like receptor, G-protein coupled receptor 17

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

13416-1-PBS targets GPR17 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen GPR17 fusion protein Ag4106 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name G protein-coupled receptor 17
Synonyms UDP/CysLT receptor, R12, P2Y-like receptor, P2Y like receptor, G-protein coupled receptor 17
Calculated Molecular Weight 367 aa, 41 kDa
Observed Molecular Weight 50 kDa
GenBank Accession NumberBC031653
Gene Symbol GPR17
Gene ID (NCBI) 2840
RRIDAB_2279341
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13304
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPR17 is a G protein-coupled receptor (GPCR) that plays a significant role in various physiological processes, particularly in the central nervous system (CNS). GPR17 is considered a modulator of CNS myelination and is involved in reconstructing and repairing demyelinating plaques caused by ongoing inflammatory processes, such as in multiple sclerosis (MS). It is present in nerve cells and precursor oligodendrocyte cells, playing a role in the differentiation and maturation of oligodendrocytes (PMID: 32182666). GPR17 is a multifaceted GPCR with implications in immune regulation, glucose metabolism, neurodegenerative diseases, and potentially in treating anxiety disorders.