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  • Featured Product
  • KD/KO Validated

GRK5 Polyclonal antibody, PBS Only

GRK5 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17032-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 17032-1-AP (same clone as 17032-1-PBS)

    WB analysis using 17032-1-AP (same clone as 17032-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17032-1-AP (GRK5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

  • IHC staining of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

    IHC staining of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 17032-1-AP (GRK5 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GRK5 antibody included
  • IHC staining of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

    IHC staining of human skeletal muscle using 17032-1-AP (same clone as 17032-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 17032-1-AP (GRK5 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 17032-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GRK5 antibody included
Planning an IHC experiment? We recommend our IHCeasy GRK5 Ready-To-Use IHC Kit. GRK5 primary antibody included.

产品信息

17032-1-PBS targets GRK5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen GRK5 fusion protein Ag10511 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name G protein-coupled receptor kinase 5
Synonyms
Calculated Molecular Weight 590 aa, 68 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC064506
Gene Symbol GRK5
Gene ID (NCBI) 2869
RRIDAB_2115453
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP34947
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GRK5, also named as GPRK5, belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and GPRK subfamily. It is Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Phosphorylation of ARRB1 by GRK5 inhibits G-protein independent MAPK1/MAPK3 signaling downstream of 5HT4-receptors. GRK5 is crucial for proper neuronal morphogenesis and the establishment of functional neuronal circuitry.