验证数据展示
产品信息
82920-1-PBS targets GSDMA in Indirect ELISA, WB applications and shows reactivity with human samples.
| 经测试应用 | Indirect ELISA, WB Application Description |
| 经测试反应性 | human |
| 免疫原 | GSDMA fusion protein Ag24407 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | gasdermin A |
| 别名 | Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9 |
| 计算分子量 | 445 aa, 49 kDa |
| 观测分子量 | 49 kDa |
| GenBank蛋白编号 | BC109197 |
| 基因名称 | GSDMA |
| Gene ID (NCBI) | 284110 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q96QA5 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.