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GSDMA Recombinant antibody, PBS Only

GSDMA Uni-rAbTM Recombinant Antibody for Indirect ELISA, WB

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

230161D4

Cat no : 82920-1-PBS

Print datasheet

Synonyms

Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9

验证数据展示

  • WB analysis of Daudi using 82920-1-RR (same clone as 82920-1-PBS)

    WB analysis of Daudi using 82920-1-RR (same clone as 82920-1-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 82920-1-RR (GSDMA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82920-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82920-1-RR

    Affinity and Kinetic Characterization of 82920-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82920-1-RR against Human GSDMA were performed. The affinity constant is below 1 pM.

产品信息

82920-1-PBS targets GSDMA in Indirect ELISA, WB applications and shows reactivity with human samples.

Tested Applications Indirect ELISA, WB Application Description
Tested Reactivity human
Immunogen GSDMA fusion protein Ag24407 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name gasdermin A
Synonyms Gasdermin-A, Gasdermin-1, gasdermin A, Gasdermin 1, FKSG9
Calculated Molecular Weight 445 aa, 49 kDa
Observed Molecular Weight49 kDa
GenBank Accession NumberBC109197
Gene Symbol GSDMA
Gene ID (NCBI) 284110
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96QA5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Gasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.