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GSDMD Recombinant antibody, PBS Only

GSDMD Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2N24

Cat No : 80918-1-PBS

Print datasheet

Synonyms

DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1

验证数据展示

  • WB analysis using 80918-1-RR (same clone as 80918-1-PBS)

    WB analysis using 80918-1-RR (same clone as 80918-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 80918-1-RR (GSDMD antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80918-1-PBS in a different storage buffer formulation.

产品信息

80918-1-PBS targets GSDMD in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse
Immunogen GSDMD fusion protein Ag14757 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name gasdermin D
Synonyms DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1
Calculated Molecular Weight 484 aa, 53 kDa
Observed Molecular Weight50-53 kDa
GenBank Accession NumberBC008904
Gene Symbol GSDMD
Gene ID (NCBI) 79792
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP57764
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.