验证数据展示
产品信息
68210-1-PBS targets GSTM5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat, pig, rabbit |
免疫原 | GSTM5 fusion protein Ag6054 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | glutathione S-transferase mu 5 |
别名 | glutathione S transferase mu 5, GST class mu 5, GSTM5, GSTM5 5, GTM5 |
计算分子量 | 26 kDa |
观测分子量 | 26 kDa |
GenBank蛋白编号 | BC058881 |
基因名称 | GSTM5 |
Gene ID (NCBI) | 2949 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P46439 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GSTM5, Glutathione S-transferases, belongs to eukaryotic and prokaryotic phase II metabolic isozymes family. It can catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for detoxification. GSTM5 undergo epigenetic repression in AMD (age-related macular degeneration) RPE/choroid, which may increase susceptibility to oxidative stress in AMD retinas (PMID: 22410570). GSTM5 was found in brain, lung and testis (PMID: 9230131).