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验证数据展示

  • WB analysis of Caco-2 using 67782-1-Ig (same clone as 67782-1-PBS)

    WB analysis of Caco-2 using 67782-1-Ig (same clone as 67782-1-PBS)

    Caco-2 cells were subjected to SDS PAGE followed by western blot with 67782-1-Ig (GUCY2C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67782-1-PBS in a different storage buffer formulation.

GUCY2C Monoclonal antibody, PBS Only

GUCY2C Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67782-1-PBS

产品说明书

CloneNo. 1F5F6

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, Indirect ELISA

别名

GC C, Guanylyl cyclase C, GUC2C, GUCY2C, hSTAR, Intestinal guanylate cyclase, STA receptor, STAR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67782-1-PBS targets GUCY2C in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 GUCY2C fusion protein Ag19256 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 guanylate cyclase 2C (heat stable enterotoxin receptor)
别名 GC C, Guanylyl cyclase C, GUC2C, GUCY2C, hSTAR, Intestinal guanylate cyclase, STA receptor, STAR
计算分子量 1073 aa, 123 kDa
观测分子量130 kDa
GenBank蛋白编号BC136544
基因名称 GUCY2C
Gene ID (NCBI) 2984
RRIDAB_2918546
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP25092
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GUCY2C is also named as GUC2C, STAR(Heat-stable enterotoxin receptor), Guanylyl cyclase C and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the E.coli heat-stable enterotoxin and considered to be the true apical membrane receptor for the endogenous ligands uroguanylin and guanylin. GUCY2C is not present in the endocrine pancreas, but is localized exclusively to the ductal system which fully corresponds to the GUCY2C activity detected in the exocrine ductal system, but particularly not in islets of Langerhans. GUCY2C with a molecular mass of 130 kDa is detected in pancreatic and intestinal extracts.(PMID:11431160). The full length protein is 123 kDa and has a signal peptide and nine glycosylation sites.