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H6PD Recombinant antibody, PBS Only

H6PD Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3C14

Cat no : 82819-2-PBS

Print datasheet

Synonyms

6PGL, DKFZp686A01246, G6PDH, GDH, H6PD

验证数据展示

  • WB analysis using 82819-2-RR (same clone as 82819-2-PBS)

    WB analysis using 82819-2-RR (same clone as 82819-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82819-2-RR (H6PD antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82819-2-PBS in a different storage buffer formulation.

产品信息

82819-2-PBS targets H6PD in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, rat
Immunogen H6PD fusion protein Ag7109 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms 6PGL, DKFZp686A01246, G6PDH, GDH, H6PD
Calculated Molecular Weight 89 kDa
Observed Molecular Weight 89-95 kDa
GenBank Accession NumberBC081559
Gene Symbol H6PD
Gene ID (NCBI) 9563
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO95479
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Hexose-6-phosphate dehydrogenase (H6PD) is also named as GDH,6PGL. It is the main NADPH generating enzyme in the lumen of the endoplasmic reticulum. H6PD is regarded as an ancillary enzyme in prereceptorial glucocorticoid activation and probably acts as a nutrient sensor and as a prosurvival factor(PMID:21620971). H6PD is a glycoprotein and has been shown tissue differences in glycosylation status might explain both the difference in migration on SDS-PAGE gels as well as in activity. Defects in H6PD are a cause of cortisone reductase deficiency (CRD).