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  • Featured Product
  • KD/KO Validated

HBP1 Polyclonal antibody, PBS Only

HBP1 Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11746-1-PBS

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Synonyms

验证数据展示

  • WB analysis of human brain using 11746-1-AP (same clone as 11746-1-PBS)

    WB analysis of human brain using 11746-1-AP (same clone as 11746-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 11746-1-AP (HBP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11746-1-PBS in a different storage buffer formulation.

  • WB analysis using 11746-1-AP (same clone as 11746-1-PBS)

    WB analysis using 11746-1-AP (same clone as 11746-1-PBS)

    SGC-7901 cells were subjected to SDS PAGE followed by western blot with 11746-1-AP (HBP1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11746-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 11746-1-AP (same clone as 11746-1-PBS)

    IP experiment of mouse brain using 11746-1-AP (same clone as 11746-1-PBS)

    IP result of anti-HBP1 (IP:11746-1-AP, 4ug; Detection:11746-1-AP 1:500) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 11746-1-PBS in a different storage buffer formulation.

产品信息

11746-1-PBS targets HBP1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen HBP1 fusion protein Ag2342 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name HMG-box transcription factor 1
Synonyms
Calculated Molecular Weight 514 aa, 58 kDa
Observed Molecular Weight 58 kDa
GenBank Accession NumberBC022329
Gene Symbol HBP1
Gene ID (NCBI) 26959
RRIDAB_2247970
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO60381
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HMG-box protein 1 (HBP1) is a transcriptional repressor, and has a role in cell cycle progression and tumor suppression. Also it's a repressor of the cyclin D1 gene and inhibits the Wnt signaling pathway. Interaction with RB1 enhances it's binding to the H1F0 promoter . Disrupts the interaction between DNA and TCF4. This is a rabbit polyclonal antibody raised against part of C-terminus of HBP1 of human origin.