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验证数据展示

  • WB analysis using 66838-1-Ig (same clone as 66838-1-PBS)

    WB analysis using 66838-1-Ig (same clone as 66838-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66838-1-Ig (HDAC4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66838-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66838-1-Ig (same clone as 66838-1-PBS)

    IHC staining of human breast cancer using 66838-1-Ig (same clone as 66838-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66838-1-Ig (HDAC4 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66838-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with HDAC4 antibody included
  • IF Staining of mouse liver using 66838-1-Ig (same clone as 66838-1-PBS)

    IF Staining of mouse liver using 66838-1-Ig (same clone as 66838-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse liver tissue using HDAC4 antibody (66838-1-Ig, Clone: 1D2G12 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66838-1-PBS in a different storage buffer formulation.

  • IF Staining of C2C12 using 66838-1-Ig (same clone as 66838-1-PBS)

    IF Staining of C2C12 using 66838-1-Ig (same clone as 66838-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed C2C12 cells using HDAC4 antibody (66838-1-Ig, Clone: 1D2G12 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 66838-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

HDAC4 Monoclonal antibody, PBS Only

HDAC4 Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, Indirect ELISA
Cat No. 66838-1-PBS

产品说明书

CloneNo. 1D2G12

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse

应用

WB, IHC, IF/ICC, IF-P, Indirect ELISA

别名

KIAA0288, HD4, EC:3.5.1.98, 1D2G12

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy HDAC4 Ready-To-Use IHC Kit. HDAC4 primary antibody included.

产品信息

66838-1-PBS targets HDAC4 in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF/ICC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 HDAC4 fusion protein Ag11345 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 histone deacetylase 4
别名 KIAA0288, HD4, EC:3.5.1.98, 1D2G12
计算分子量 972 aa, 106 kDa
观测分子量 140 kDa
GenBank蛋白编号BC039904
基因名称 HDAC4
Gene ID (NCBI) 9759
RRIDAB_2882181
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP56524
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HDAC4, also named as HDACA, belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.