验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 67364-1-Ig
产品信息
CL488-67364 targets HDAC9 in applications and shows reactivity with Human samples.
| 经测试应用 | Application Description |
| 经测试反应性 | Human |
| 免疫原 | HDAC9 fusion protein Ag28514 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | histone deacetylase 9 |
| 别名 | HD9, HDRP, HDAC7B, HDAC7, EC:3.5.1.98 |
| 计算分子量 | 1011 aa, 111 kDa |
| 观测分子量 | 130 kDa |
| GenBank蛋白编号 | BC152405 |
| 基因名称 | HDAC9 |
| Gene ID (NCBI) | 9734 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9UKV0 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HDAC9, also named as Histone deacetylase 7B, is a 1011 amino acid protein, which is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC9 represses MEF2-dependent transcription. HDAC9 is broadly expressed, with highest levels in brain, heart, muscle and testis.