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验证数据展示

  • WB analysis of Caco-2 using 66311-1-Ig (same clone as 66311-1-PBS)

    WB analysis of Caco-2 using 66311-1-Ig (same clone as 66311-1-PBS)

    Caco-2 cells were subjected to SDS PAGE followed by western blot with 66311-1-Ig (HEXIM1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66311-1-PBS in a different storage buffer formulation.

  • WB analysis using 66311-1-Ig (same clone as 66311-1-PBS)

    WB analysis using 66311-1-Ig (same clone as 66311-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66311-1-Ig (HEXIM1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66311-1-PBS in a different storage buffer formulation.

HEXIM1 Monoclonal antibody, PBS Only

HEXIM1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66311-1-PBS

产品说明书

CloneNo. 2C8A2

宿主/亚型

Mouse / IgM

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

Hexamethylene bis-acetamide-inducible protein 1, Estrogen down-regulated gene 1 protein, EDG1, CLP1, CLP 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.

Planning an IHC experiment? We recommend our IHCeasy HEXIM1 Ready-To-Use IHC Kit. HEXIM1 primary antibody included.

产品信息

66311-1-PBS targets HEXIM1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 HEXIM1 fusion protein Ag8019 种属同源性预测
宿主/亚型 Mouse / IgM
抗体类别 Monoclonal
产品类型 Antibody
全称 hexamethylene bis-acetamide inducible 1
别名 Hexamethylene bis-acetamide-inducible protein 1, Estrogen down-regulated gene 1 protein, EDG1, CLP1, CLP 1
计算分子量 41 kDa
观测分子量 54 kDa
GenBank蛋白编号BC006460
基因名称 HEXIM1
Gene ID (NCBI) 10614
RRIDAB_2881693
偶联类型 Unconjugated
形式 Liquid
纯化方式Thiophilic affinity chromatograph
UNIPROT IDO94992
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway.The mainstream MW of this protein is 65-70 kDa and 54 kDa ( PMID: 33627647, PMID: 20976203, PMID: 28254838).