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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 30022-1-AP (same clone as 30022-1-PBS)

    WB analysis using 30022-1-AP (same clone as 30022-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30022-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30022-1-PBS in a different storage buffer formulation.

  • WB analysis using 30022-1-AP (same clone as 30022-1-PBS)

    WB analysis using 30022-1-AP (same clone as 30022-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30022-1-AP (HIP14; ZDHHC17 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30022-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 30022-1-AP (same clone as 30022-1-PBS)

    IF Staining of U2OS using 30022-1-AP (same clone as 30022-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using HIP14; ZDHHC17 antibody (30022-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30022-1-PBS in a different storage buffer formulation.

HIP14; ZDHHC17 Polyclonal antibody, PBS Only

HIP14; ZDHHC17 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 30022-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

ZDHHC17, HIP 14, EC:2.3.1.225, EC:2.3.1.-, DHHC domain-containing cysteine-rich protein 17

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

30022-1-PBS targets HIP14; ZDHHC17 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 HIP14; ZDHHC17 fusion protein Ag32654 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 zinc finger, DHHC-type containing 17
别名 ZDHHC17, HIP 14, EC:2.3.1.225, EC:2.3.1.-, DHHC domain-containing cysteine-rich protein 17
计算分子量 73 kDa
观测分子量 70 kDa
GenBank蛋白编号BC050324
基因名称 ZDHHC17
Gene ID (NCBI) 23390
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8IUH5
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ZDHHC17 is a neuronal palmitoyl transferase. Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.