验证数据展示
产品信息
84769-1-PBS targets HMGCL as part of a matched antibody pair:
MP01555-2: 84769-2-PBS capture and 84769-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Applications | WB, Cytometric bead array, Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | HMGCL fusion protein Ag10426 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase |
| Synonyms | HMG-CoA lyase, HMG CoA lyase, HL, EC:4.1.3.4, 242224G10 |
| Calculated Molecular Weight | 325 aa, 34 kDa |
| Observed Molecular Weight | 32 kDa |
| GenBank Accession Number | BC010570 |
| Gene Symbol | HMGCL |
| Gene ID (NCBI) | 3155 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P35914 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) is a key enzyme in ketogenesis (ketone body formation). It is a ketogenic enzyme in the liver that catalyzes the formation of acetoacetate from HMG-CoA within the mitochondria. It also plays a prominent role in the catabolism of the amino acid leucine.