验证数据展示
Planning an IHC experiment? We recommend our IHCeasy HNF1B Ready-To-Use IHC Kit. HNF1B primary antibody included.
产品信息
84684-4-PBS targets HNF1B in WB, Indirect ELISA applications and shows reactivity with human, canine samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, canine |
| 免疫原 | HNF1B fusion protein Ag3232 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | HNF1 homeobox B |
| 别名 | TCF2, HNF-1-beta, HNF-1B, HNF 1 beta, Hepatocyte nuclear factor 1-beta |
| 计算分子量 | 557 aa, 61 kDa |
| 观测分子量 | 58-65 kDa |
| GenBank蛋白编号 | BC017714 |
| 基因名称 | HNF1B |
| Gene ID (NCBI) | 6928 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P35680 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Hepatocyte nuclear factor-1-beta(HNF1B), or transcription factor-2(TCF2), is a member of the homeodomain-containing superfamily of transcription factors. Early expression of HNF1B(12533-1-AP) is seen in the kidney, liver, pancreas, thymus, lung, gut and genital tract. HNF1B can be a homodimer or a heterodimer with HNF1A. It's a transcription factor, probably by binding to the inverted palindrome 5'-GTTAATNATTAAC-3', and as a bookmarking factor that marks target genes for rapid transcriptional reactivation after mitosis.