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HNMT Recombinant antibody, PBS Only

HNMT Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242159E3

Cat no : 84777-3-PBS

Print datasheet

Synonyms

HNMT S1, HMT, Histamine N-methyltransferase, histamine N methyltransferase, EC:2.1.1.8

验证数据展示

  • WB analysis using 84777-3-RR (same clone as 84777-3-PBS)

    WB analysis using 84777-3-RR (same clone as 84777-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84777-3-RR (HNMT antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84777-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84777-3-RR

    Affinity and Kinetic Characterization of 84777-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84777-3-RR against Human HNMT were performed. The affinity constant is below 1 pM.

产品信息

84777-3-PBS targets HNMT in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen HNMT fusion protein Ag2462 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name histamine N-methyltransferase
Synonyms HNMT S1, HMT, Histamine N-methyltransferase, histamine N methyltransferase, EC:2.1.1.8
Calculated Molecular Weight 292 aa, 33 kDa
Observed Molecular Weight 30-33 kDa
GenBank Accession NumberBC020677
Gene Symbol HNMT
Gene ID (NCBI) 3176
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP50135
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HNMT, a histamine-metabolizing enzyme, inactivates histamine by N-methylation. It plays an important role in degrading histamine and in regulating the airway response to histamine. HNMT in human astrocytes play a role in the regulation of extraneuronal histamine concentration and the activities of histaminergic neurons.