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CoraLite® Plus 488-conjugated HNRNPUL1 Polyclonal antibody

HNRNPUL1 Polyclonal Antibody for IF/ICC
Cat No. CL488-10578

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF/ICC

E1B AP5, E1BAP5, FLJ12944, HNRNPUL1, HNRPUL1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive IF/ICC detected inHepG2 cells
Planning an IHC experiment? We recommend our IHCeasy HNRNPUL1 Ready-To-Use IHC Kit. HNRNPUL1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 10578-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-10578 targets HNRNPUL1 in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原 HNRNPUL1 fusion protein Ag0899 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 heterogeneous nuclear ribonucleoprotein U-like 1
别名 E1B AP5, E1BAP5, FLJ12944, HNRNPUL1, HNRPUL1
计算分子量 120 kDa
观测分子量 90-115 kDa
GenBank蛋白编号BC002564
基因名称 HNRNPUL1
Gene ID (NCBI) 11100
RRIDAB_3672452
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BUJ2
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

HNRNPUL1, also named as E1BAP5, HNRPUL1 and E1B-AP5, acts as a basic transcriptional regulator. It represses basic transcription driven by several virus and cellular promoters. HNRNPUL1 plays also a role in mRNA processing and transport. It is a cellular protein that interacts with the adenovirus protein E1B-55 and implicated in mRNA export. HNRNPUL1 is an hnRNP-like protein that likely mediates the interaction of NXF1 with mRNAs.(PMID:17267598). It may modulate PAN expression in complex with KSHV ORF57(PMID:22043172). HNRNPUL1 specifically bound to the Rae1-Nup98 complex independently of M protein, and this interaction was found to be RNA dependent, as it was greatly diminished in the presence of RNase.(PMID:19745842) HNRNPUL1 has 5 isoforms with calculated MW 84-95kd and 42kd(isoform 5). This antibody can recognize isoform 1-4 .

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 HNRNPUL1 antibody CL488-10578Download protocol
Standard Protocols
Click here to view our Standard Protocols
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