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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
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验证数据展示

  • IHC staining of mouse testis using 10496-1-AP (same clone as 10496-1-PBS)

    IHC staining of mouse testis using 10496-1-AP (same clone as 10496-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 10496-1-AP (HOXD3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10496-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 10496-1-AP (same clone as 10496-1-PBS)

    IF Staining of U2OS using 10496-1-AP (same clone as 10496-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using HOXD3 antibody (10496-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 10496-1-PBS in a different storage buffer formulation.

HOXD3 Polyclonal antibody, PBS Only

HOXD3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 10496-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

10496-1-PBS targets HOXD3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen HOXD3 fusion protein Ag0768 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name homeobox D3
Synonyms
Calculated Molecular Weight 46 kDa
GenBank Accession NumberBC005124
Gene Symbol HOXD3
Gene ID (NCBI) 3232
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP31249
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Homeobox D3 (HOXD3), a member of the Homeobox (Hox) family of master transcription factors, is a homeobox transcription factor that promotes angiogenesis and collagen synthesis. HOXD3 is expressed during normal embryogenesis, skin development, and fetal wound healing (PMID: 14633614). The overexpression of HOXD3 plays a critical role in breast cancer stemness and drug resistance via integrin β3-mediated Wnt/β-catenin signaling (PMID: 29698974).