验证数据展示
产品信息
10496-1-PBS targets HOXD3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | HOXD3 fusion protein Ag0768 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | homeobox D3 |
别名 | |
计算分子量 | 46 kDa |
GenBank蛋白编号 | BC005124 |
基因名称 | HOXD3 |
Gene ID (NCBI) | 3232 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P31249 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Homeobox D3 (HOXD3), a member of the Homeobox (Hox) family of master transcription factors, is a homeobox transcription factor that promotes angiogenesis and collagen synthesis. HOXD3 is expressed during normal embryogenesis, skin development, and fetal wound healing (PMID: 14633614). The overexpression of HOXD3 plays a critical role in breast cancer stemness and drug resistance via integrin β3-mediated Wnt/β-catenin signaling (PMID: 29698974).