验证数据展示
产品信息
29685-1-PBS targets HTR3A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | HTR3A fusion protein Ag31317 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | 5-hydroxytryptamine (serotonin) receptor 3A |
别名 | |
计算分子量 | 55 kDa |
观测分子量 | 55 kDa |
GenBank蛋白编号 | BC002354 |
基因名称 | HTR3A |
Gene ID (NCBI) | 3359 |
RRID | AB_2918338 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P46098 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HTR3A (5-hydroxytryptamine receptor 3A, 5-HT3A) belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (5-HT, serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. So far, five distinct 5-HT3 receptor subunits (A-E) have been identified. HTR3A can form functional homomers or heteromers with HTR3B or HTR3C or HTR3D or HTR3E. 5-HT3 receptors are capable of mediating fast excitatory neurotransmission in the CNS and peripheral nervous system (PNS). (PMID: 23038271; 17073663)