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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

HTR7 Polyclonal antibody, PBS Only

HTR7 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13830-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

13830-1-PBS targets HTR7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 HTR7 fusion protein Ag4742 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
别名
计算分子量 445 aa, 49 kDa
观测分子量 50-55 kDa
GenBank蛋白编号BC047526
基因名称 HTR7
Gene ID (NCBI) 3363
RRIDAB_2122706
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP34969
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Serotonin (5-hydroxytryptamine; 5-HT) acts as a neurotransmitter and neuromodulator in the central nervous system(CNS) (PMID:23100172). The behavioral effects of 5-HT are mediated by a large family of specific 5-HT receptors. HTR7 (5-hydroxytryptamine receptor 7) is a G protein-coupled receptor (GPCR), and many transcription factors can bind to its promoter, such as AP2, EGR-1, and MAZ (PMID:34164474). It is located in different brain regions, such as the hypothalamus, thalamus, cerebral cortex, and hippocampus (PMID:29637287). HTR7 is associated with circadian rhythm, anxiety, depression, schizophrenia, nociception, and memory (PMID:9154233).