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HTR7 Polyclonal antibody, PBS Only

HTR7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13830-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

产品信息

13830-1-PBS targets HTR7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen HTR7 fusion protein Ag4742 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
Synonyms
Calculated Molecular Weight 445 aa, 49 kDa
Observed Molecular Weight 50-55 kDa
GenBank Accession NumberBC047526
Gene Symbol HTR7
Gene ID (NCBI) 3363
RRIDAB_2122706
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP34969
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Serotonin (5-hydroxytryptamine; 5-HT) acts as a neurotransmitter and neuromodulator in the central nervous system(CNS) (PMID:23100172). The behavioral effects of 5-HT are mediated by a large family of specific 5-HT receptors. HTR7 (5-hydroxytryptamine receptor 7) is a G protein-coupled receptor (GPCR), and many transcription factors can bind to its promoter, such as AP2, EGR-1, and MAZ (PMID:34164474). It is located in different brain regions, such as the hypothalamus, thalamus, cerebral cortex, and hippocampus (PMID:29637287). HTR7 is associated with circadian rhythm, anxiety, depression, schizophrenia, nociception, and memory (PMID:9154233).