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验证数据展示

  • WB analysis using 81719-2-RR (same clone as 81719-2-PBS)

    WB analysis using 81719-2-RR (same clone as 81719-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 81719-2-RR (Hsc70 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81719-2-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 81719-2-RR (same clone as 81719-2-PBS)

    WB analysis of HeLa using 81719-2-RR (same clone as 81719-2-PBS)

    WB result of Hsc70 antibody (81719-2-RR; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Hsc70 transfected HeLa cells. This data was developed using the same antibody clone with 81719-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

Hsc70 Recombinant antibody, PBS Only

Hsc70 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 81719-2-PBS

产品说明书

CloneNo. 3H9

宿主/亚型

Rabbit / IgG

种属反应性

Human, mouse, rat

应用

WB, Indirect ELISA

别名

Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP1, NIP71

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy HSC70/HSPA8 Ready-To-Use IHC Kit. HSC70/HSPA8 primary antibody included.

产品信息

81719-2-PBS targets Hsc70 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 Hsc70 fusion protein Ag1018 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 heat shock 70kDa protein 8
别名 Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP1, NIP71
计算分子量 70 kDa
观测分子量 70 kDa
GenBank蛋白编号BC007276
基因名称 HSC70
Gene ID (NCBI) 3312
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP11142
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson's disease, indicating its implication in neurodegenerative disease. (PMID: 21832061)