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验证数据展示

  • WB analysis using 66045-1-Ig (same clone as 66045-1-PBS)

    WB analysis using 66045-1-Ig (same clone as 66045-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66045-1-Ig (IA-2/PTPRN antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66045-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 66045-1-Ig (same clone as 66045-1-PBS)

    IHC staining of human pancreas cancer using 66045-1-Ig (same clone as 66045-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 66045-1-Ig (IA-2/PTPRN antibody at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66045-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PTPRN antibody included
  • IHC staining of human pancreas cancer using 66045-1-Ig (same clone as 66045-1-PBS)

    IHC staining of human pancreas cancer using 66045-1-Ig (same clone as 66045-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 66045-1-Ig (IA-2/PTPRN antibody at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66045-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PTPRN antibody included
  • IF Staining of HepG2 using 66045-1-Ig (same clone as 66045-1-PBS)

    IF Staining of HepG2 using 66045-1-Ig (same clone as 66045-1-PBS)

    Immunofluorescent analysis of HepG2 cells using 66045-1-Ig (IA-2/PTPRN antibody) at dilution of 1:25 and Rhodamine-Goat anti-Mouse IgG. This data was developed using the same antibody clone with 66045-1-PBS in a different storage buffer formulation.

  • WB analysis of human brain using 66045-1-Ig (same clone as 66045-1-PBS)

    WB analysis of human brain using 66045-1-Ig (same clone as 66045-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 66045-1-Ig (IA-2/PTPRN antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66045-1-PBS in a different storage buffer formulation.

IA-2/PTPRN Monoclonal antibody, PBS Only

IA-2/PTPRN Monoclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 66045-1-PBS

产品说明书

CloneNo. 1D3F5

宿主/亚型

Mouse / IgG3

种属反应性

human, pig, rabbit

应用

WB, IHC, IF/ICC, ELISA

别名

IA-2, PTPRN, 1D3F5, ICA512-transmembrane fragment, ICA512-N-terminal fragment

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PTPRN Ready-To-Use IHC Kit. PTPRN primary antibody included.

产品信息

66045-1-PBS targets IA-2/PTPRN in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, pig, rabbit samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
经测试反应性 human, pig, rabbit
免疫原 IA-2/PTPRN fusion protein Ag17909 种属同源性预测
宿主/亚型 Mouse / IgG3
抗体类别 Monoclonal
产品类型 Antibody
全称 protein tyrosine phosphatase, receptor type, N
别名 IA-2, PTPRN, 1D3F5, ICA512-transmembrane fragment, ICA512-N-terminal fragment
计算分子量 105 kDa
观测分子量 60-65 kDa, 106-115 kDa
GenBank蛋白编号BC007713
基因名称 IA-2/PTPRN
Gene ID (NCBI) 5798
RRIDAB_11064603
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ16849
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family, which contains a transmembrane region, an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.