IDH1 Recombinant antibody, PBS Only
IDH1 Recombinant Antibody for WB,Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse, rat
Applications
WB,Indirect ELISA
Conjugate
Unconjugated
CloneNo.
6L18
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy IDH1 Ready-To-Use IHC Kit. IDH1 primary antibody included.
产品信息
81176-1-PBS targets IDH1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| Tested Applications | WB,Indirect ELISA Application Description |
| Tested Reactivity | Human, mouse, rat |
| Immunogen | IDH1 fusion protein Ag19749 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | isocitrate dehydrogenase 1 (NADP+), soluble |
| Synonyms | IDCD, IDH, IDH1, IDP, IDPC, NADP(+) specific ICDH, Oxalosuccinate decarboxylase, PICD |
| Calculated Molecular Weight | 414 aa, 47 kDa |
| Observed Molecular Weight | 46 kDa |
| GenBank Accession Number | BC012846 |
| Gene Symbol | IDH1 |
| Gene ID (NCBI) | 3417 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O75874 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
背景介绍
IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171). IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).