IFNGR1 Monoclonal antibody, PBS Only

IFNGR1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66704-1-PBS

产品说明书

CloneNo. 1H3A4

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

WB, Indirect ELISA

IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1, CD119

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

66704-1-PBS targets IFNGR1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 IFNGR1 fusion protein Ag27085 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 interferon gamma receptor 1
别名 IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1, CD119
计算分子量 54 kDa
观测分子量 90 kDa
GenBank蛋白编号BC005333
基因名称 IFNGR1
Gene ID (NCBI) 3459
RRIDAB_2882056
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP15260
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interferon-gamma (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)

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