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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 13981-1-AP (same clone as 13981-1-PBS)

    WB analysis using 13981-1-AP (same clone as 13981-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13981-1-AP (IGFBP1 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13981-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 13981-1-AP (same clone as 13981-1-PBS)

    IHC staining of human lung cancer using 13981-1-AP (same clone as 13981-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13981-1-AP (IGFBP1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13981-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with IGFBP1 antibody included

IGFBP1 Polyclonal antibody, PBS Only

IGFBP1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13981-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy IGFBP1 Ready-To-Use IHC Kit. IGFBP1 primary antibody included.

产品信息

13981-1-PBS targets IGFBP1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 IGFBP1 fusion protein Ag5026 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 IGF binding protein 1
别名
计算分子量 28 kDa
观测分子量 28-35 kDa
GenBank蛋白编号BC057806
基因名称 IGFBP1
Gene ID (NCBI) 3484
RRIDAB_2233481
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP08833
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IGF-binding proteins (IGFBPs) family contains members like IGFBP-1, -2, -3, -4,-5 and-6. IGFBPs prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGF-I physically interacts with IGFBP-1 and that IGFBP-1 also binds to an integrin receptor, but the effect of IGFBP-1 on cell migration may be independent of IGF-I and is probably mediated through the alpha 5 beta 1 integrin. Transgenic mice models demonstrated that IGFBPs played important roles in the pathogenesis of obesity and INS resistance. Studies conducted in humans demonstrated the close relation between IGFBPs and the components of the metabolic syndrome.