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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 82696-17-RR (same clone as 82696-17-PBS)

    WB analysis using 82696-17-RR (same clone as 82696-17-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82696-17-RR (IL-1 beta antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82696-17-PBS in a different storage buffer formulation.

  • WB analysis of THP-1 using 82696-17-RR (same clone as 82696-17-PBS)

    WB analysis of THP-1 using 82696-17-RR (same clone as 82696-17-PBS)

    LPS and Brefeldin A treated THP-1 cells were subjected to SDS PAGE followed by western blot with 82696-17-RR (IL-1 beta antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82696-17-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82696-17-RR

    Affinity and Kinetic Characterization of 82696-17-RR

    Biolayer interferometry (BLl) kinetic assays of 82696-17-RR against Human IL-1 beta were performed. The affinity constant is 60.2 nM.

IL-1 beta Recombinant antibody, PBS Only

IL-1 beta Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 82696-17-PBS

产品说明书

CloneNo. 240902G6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

IL1- beta, IL1 beta, IL 1 beta, IL 1, Catabolin

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

82696-17-PBS targets IL-1 beta in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 1, beta
别名 IL1- beta, IL1 beta, IL 1 beta, IL 1, Catabolin
计算分子量 269 aa, 31 kDa
观测分子量35 kDa
GenBank蛋白编号BC008678
基因名称 IL1B
Gene ID (NCBI) 3553
ENSEMBL Gene IDENSG00000125538
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP01584
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to the activation of numerous downstream targets.