验证数据展示
产品信息
98149-1-PBS targets IL-12RB1/CD212 in FC applications and shows reactivity with human samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | human |
| Immunogen | Recombinant Protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | interleukin 12 receptor, beta 1 |
| Synonyms | IL12RB1, IL-12 receptor beta component, IL 12RB1, IL 12R subunit beta 1, IL 12R beta 1 |
| Calculated Molecular Weight | 662 aa, 73 kDa |
| GenBank Accession Number | BC029121 |
| Gene Symbol | IL12RB1 |
| Gene ID (NCBI) | 3594 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | P42701 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Interleukin-12 receptor subunit beta-1 (IL-12RB1), also named as CD212, is a 662 amino acid protein, which contains 5 fibronectin type-III domains and belongs to the type I cytokine receptor family. IL-12RB1 localizes in the membrane and functions as an interleukin receptor which binds IL-12 with low affinity and is involved in IL-12 transduction. Associated with IL-12RB2 it forms a functional, high affinity receptor for IL-12. It can also associate with IL23R to form the interleukin-23 receptor which functions in IL-23 signal transduction probably through activation of the Jak-Stat signaling cascade.