验证数据展示
经过测试的应用
Positive FC (Intra) detected in | PMA, Ionomycin and Brefeldin A treated human PBMCs |
推荐稀释比
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
98053-1-RR targets IL-2 in FC (Intra) applications and shows reactivity with human samples.
Tested Applications | FC (Intra) Application Description |
Tested Reactivity | human |
Immunogen | Fusion Protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | interleukin 2 |
Synonyms | IL2, TCGF, Interleukin-2, interleukin 2, IL 2 |
Calculated Molecular Weight | 153 aa, 18 kDa |
GenBank Accession Number | BC070338 |
Gene Symbol | IL2 |
Gene ID (NCBI) | 3558 |
RRID | AB_3672200 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P60568 |
Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Interleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641).
实验方案
Product Specific Protocols | |
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FC protocol for IL-2 antibody 98053-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |