验证数据展示
产品信息
66319-1-PBS targets IL-21R in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | IL-21R fusion protein Ag21295 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | interleukin 21 receptor |
Synonyms | IL21R, IL-21 receptor, IL 21R, IL 21 receptor, CD360 |
Calculated Molecular Weight | 59 kDa |
Observed Molecular Weight | 55-65 kDa |
GenBank Accession Number | BC004348 |
Gene Symbol | IL-21R |
Gene ID (NCBI) | 50615 |
RRID | AB_2881700 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9HBE5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.