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IL-21R Monoclonal antibody, PBS Only

IL-21R Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1D1C2

Cat No : 66319-1-PBS

Print datasheet

Synonyms

CD360, IL 21 receptor, IL 21R, IL21R, IL-21R, interleukin 21 receptor, NILR, Novel interleukin receptor

验证数据展示

  • WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

    WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

    IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66319-1-Ig (IL21R antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

    IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66319-1-Ig (IL21R antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

产品信息

66319-1-PBS targets IL-21R in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen IL-21R fusion protein Ag21295 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name interleukin 21 receptor
Synonyms CD360, IL 21 receptor, IL 21R, IL21R, IL-21R, interleukin 21 receptor, NILR, Novel interleukin receptor
Calculated Molecular Weight 59 kDa
Observed Molecular Weight 55-65 kDa
GenBank Accession NumberBC004348
Gene Symbol IL-21R
Gene ID (NCBI) 50615
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9HBE5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.