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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

    WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

    IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

    IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

IL-23R Polyclonal antibody, PBS Only

IL-23R Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 27163-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

IL23R, Interleukin-23 receptor, interleukin 23 receptor, IL-23 receptor, IL 23R

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

27163-1-PBS targets IL-23R in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 IL-23R fusion protein Ag25939 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin 23 receptor
别名 IL23R, Interleukin-23 receptor, interleukin 23 receptor, IL-23 receptor, IL 23R
计算分子量 72 kDa
观测分子量 65-75 kDa
GenBank蛋白编号 NM_144701
基因名称 IL-23R
Gene ID (NCBI) 149233
RRIDAB_2880783
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-23 receptor (IL-23R) is a type I cytokine receptor that plays a critical role in immune responses and inflammation. It forms a receptor complex with IL-12Rβ1 and is activated by the cytokine IL-23, which is primarily produced by dendritic cells and activated macrophages (PMID: 39796684). The genetic and epigenetic interactions in the IL-23R/IL-17 axis are associated with elevated expression of IL-17 and inflammatory bowel disease (IBD) pathogenesis (PMID: 21672939).