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ING2 Monoclonal antibody, PBS Only

ING2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C3A7

Cat no : 66512-1-PBS

Print datasheet

Synonyms

ING1L, ING1Lp, ING2, Inhibitor of growth protein 2, p32, p33ING2

验证数据展示

  • WB analysis of HSC-T6 using 66512-1-Ig (same clone as 66512-1-PBS)

    WB analysis of HSC-T6 using 66512-1-Ig (same clone as 66512-1-PBS)

    HSC-T6 cells were subjected to SDS PAGE followed by western blot with 66512-1-Ig (ING2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66512-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy ING2 Ready-To-Use IHC Kit. ING2 primary antibody included.

产品信息

66512-1-PBS targets ING2 in WB, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, rat, mouse
Immunogen ING2 fusion protein Ag19291 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name inhibitor of growth family, member 2
Synonyms ING1L, ING1Lp, ING2, Inhibitor of growth protein 2, p32, p33ING2
Calculated Molecular Weight 280 aa, 33 kDa
Observed Molecular Weight 33-35 kDa
GenBank Accession NumberBC030128
Gene Symbol ING2
Gene ID (NCBI) 3622
RRIDAB_2881875
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9H160
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program.