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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis of A549 using 66835-1-Ig (same clone as 66835-1-PBS)

    WB analysis of A549 using 66835-1-Ig (same clone as 66835-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

IRF5 Monoclonal antibody, PBS Only

IRF5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66835-1-PBS

产品说明书

CloneNo. 3A4A10

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse

应用

WB, Indirect ELISA

别名

interferon regulatory factor 5, IRF 5, IRF5, SLEB10

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66835-1-PBS targets IRF5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse
免疫原 IRF5 fusion protein Ag5442 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interferon regulatory factor 5
别名 interferon regulatory factor 5, IRF 5, IRF5, SLEB10
计算分子量 56 kDa
观测分子量 56 kDa
GenBank蛋白编号BC004201
基因名称 IRF5
Gene ID (NCBI) 3663
RRIDAB_2882178
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ13568
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. It is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). IRF5 is also used as M1 marcrophage lineage marker. Alternative splice variant encoding different isoforms exist.