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IRF5 Monoclonal antibody, PBS Only

IRF5 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3A4A10

Cat no : 66835-1-PBS

Print datasheet

Synonyms

interferon regulatory factor 5, IRF 5, IRF5, SLEB10

验证数据展示

  • WB analysis of A549 using 66835-1-Ig (same clone as 66835-1-PBS)

    WB analysis of A549 using 66835-1-Ig (same clone as 66835-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

产品信息

66835-1-PBS targets IRF5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse
Immunogen IRF5 fusion protein Ag5442 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name interferon regulatory factor 5
Synonyms interferon regulatory factor 5, IRF 5, IRF5, SLEB10
Calculated Molecular Weight 56 kDa
Observed Molecular Weight 56 kDa
GenBank Accession NumberBC004201
Gene Symbol IRF5
Gene ID (NCBI) 3663
RRIDAB_2882178
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ13568
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. It is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). IRF5 is also used as M1 marcrophage lineage marker. Alternative splice variant encoding different isoforms exist.