IRF5 Monoclonal antibody

IRF5 Monoclonal Antibody for WB, ELISA
Cat No. 66835-1-Ig

产品说明书

CloneNo. 3A4A10

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse

应用

WB, ELISA

interferon regulatory factor 5, IRF 5, IRF5, SLEB10

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive WB detected inA549 cells, HeLa cells, THP-1 cells, RAW 264.7 cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

66835-1-Ig targets IRF5 in WB, ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, mouse
免疫原 IRF5 fusion protein Ag5442 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interferon regulatory factor 5
别名 interferon regulatory factor 5, IRF 5, IRF5, SLEB10
计算分子量 56 kDa
观测分子量 56 kDa
GenBank蛋白编号BC004201
基因名称 IRF5
Gene ID (NCBI) 3663
RRIDAB_2882178
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. It is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). IRF5 is also used as M1 marcrophage lineage marker. Alternative splice variant encoding different isoforms exist.

实验方案

Product Specific Protocols
WB protocol for IRF5 antibody 66835-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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