Anti-Mouse IFN-gamma Rabbit Recombinant Antibody, PBS Only
IFN-gamma Uni-rAbTM Recombinant Antibody for FC (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
mouse
Applications
FC (Intra)
Conjugate
Unconjugated
CloneNo.
240262C9
验证数据展示
产品信息
98045-1-PBS targets IFN-gamma in FC (Intra) applications and shows reactivity with mouse samples.
| Tested Applications | FC (Intra) Application Description |
| Tested Reactivity | mouse |
| Immunogen | Fusion Protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | interferon gamma |
| Synonyms | IFN gamma, Ifng, IFN γ, IFN g, Ifg |
| Calculated Molecular Weight | 17 kDa |
| GenBank Accession Number | BC119063 |
| Gene Symbol | IFN gamma |
| Gene ID (NCBI) | 15978 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | P01580 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Interferon gamma (IFN γ), is a type II interferon that provides immunity against bacterial, viral and protozoan infections. In its active form, IFN γ is a glycosylated, non-covalently linked homodimer of 29-32 kDa subunits. It is produced by a number of immune cell types including natural killer cells, natural killer T cells, and effector lymphocyte T cells following antigenic and inflammatory triggers. The IFN γ dimer binds to its cognate receptor which has two subunits: IFN-γR1 which is the ligand-binding chain (α chain) and IFN-γR2, the signal-transducing chain (β chain). Binding to the receptor activates the JAK/STAT pathway which in turn activates IFN γ responsive genes. While IFN γ can inhibit viral replication, it also works as an immune-modulator and immune-stimulator by increasing surface expression of class I MHC proteins. (PMID: 19268625; 10688427)