验证数据展示
产品信息
66315-1-PBS targets Integrin Beta 1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | Integrin Beta 1 fusion protein Ag24476 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
Synonyms | CD29, FNRB, GPIIA, Integrin beta 1, Integrin beta-1, ITGB1, MDF2, MSK12, VLA 4 subunit beta, VLA BETA, VLAB |
Calculated Molecular Weight | 88 kDa |
Observed Molecular Weight | 130 kDa |
GenBank Accession Number | BC020057 |
Gene Symbol | Integrin beta 1 |
Gene ID (NCBI) | 3688 |
ENSEMBL Gene ID | ENSG00000150093 |
RRID | AB_2881696 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P05556 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.