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验证数据展示

  • WB analysis using 30714-1-AP (same clone as 30714-1-PBS)

    WB analysis using 30714-1-AP (same clone as 30714-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30714-1-AP (Integrin alpha-8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30714-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    IHC staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 30714-1-AP (Integrin alpha-8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30714-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    IHC staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 30714-1-AP (Integrin alpha-8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30714-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    IF Staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse lung tissue using Integrin alpha-8 antibody (30714-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30714-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    IF Staining of mouse lung using 30714-1-AP (same clone as 30714-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse lung tissue using Integrin alpha-8 antibody (30714-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30714-1-PBS in a different storage buffer formulation.

Integrin alpha-8 Polyclonal antibody, PBS Only

Integrin alpha-8 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 30714-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF-P, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

30714-1-PBS targets Integrin alpha-8 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag33507

Product name: Recombinant human Integrin alpha-8 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 791-970 aa of NM_003638

Sequence: GVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALAS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 integrin, alpha 8
别名
计算分子量117 kDa
观测分子量140 kDa
GenBank蛋白编号NM_003638
基因名称 Integrin alpha 8
Gene ID (NCBI) 8516
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP53708
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. Integrin alpha-8 is a single-pass type I membrane protein that forms a heterodimer with integrin beta-1 to serve as a receptor for RGD-containing matrix molecules (fibronectin, vitronectin, tenascin C, osteopontin, and nephronectin) (PMID: 33000355). Integrin alpha-8 beta-1 plays a critical role in epithelial-mesenchymal interactions and functions in the genesis of kidney and probably of other organs (PMID: 9054500; 19769957). The apparent molecular weight of integrin alpha-8 is larger than the calculated molecular weight of 117 kDa, possibly due to glycosylation (PMID: 7768999).

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