验证数据展示
产品信息
80331-1-PBS targets JAK3 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | Janus kinase 3 (a protein tyrosine kinase, leukocyte) |
别名 | 3N1, EC:2.7.10.2, JAK 3, JAK-3, JAKL |
计算分子量 | 1124 aa, 125 kDa |
观测分子量 | 125 kDa |
GenBank蛋白编号 | BC028068 |
基因名称 | JAK3 |
Gene ID (NCBI) | 3718 |
RRID | AB_2918888 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P52333 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
JAK3 is a non-receptor tyrosine kinase, predominantly expressed in hematopoietic cells and that has been implicated in the signal transduction of the common gamma chain subfamily of cytokine receptors. As a result, JAK3 plays an essential role in hematopoieisis during T cell development. JAK3 belongs to the Janus kinase family of receptor-associated tyrosine kinases located in cytoplasm adjacent to the plasma membrane. (PMID: 19747563, PMID: 33767339)