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Jagged1 Recombinant antibody, PBS Only

Jagged1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241412F1

Cat no : 84694-1-PBS

Print datasheet

Synonyms

JAG1, Protein jagged-1, HJ1, CD339, 241412F1

验证数据展示

  • WB analysis of HepG2 using 84694-1-RR (same clone as 84694-1-PBS)

    WB analysis of HepG2 using 84694-1-RR (same clone as 84694-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 84694-1-RR (Jagged1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84694-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84694-1-RR

    Affinity and Kinetic Characterization of 84694-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84694-1-RR against Human Jagged1 were performed. The affinity constant is 0.688 nM.

产品信息

84694-1-PBS targets Jagged1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name jagged 1 (Alagille syndrome)
Synonyms JAG1, Protein jagged-1, HJ1, CD339, 241412F1
Calculated Molecular Weight 1218 aa, 134 kDa
Observed Molecular Weight150 kDa
GenBank Accession NumberBC098393
Gene Symbol Jagged1
Gene ID (NCBI) 182
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP78504
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).