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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of HepG2 using 84694-1-RR (same clone as 84694-1-PBS)

    WB analysis of HepG2 using 84694-1-RR (same clone as 84694-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 84694-1-RR (Jagged1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84694-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84694-1-RR

    Affinity and Kinetic Characterization of 84694-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84694-1-RR against Human Jagged1 were performed. The affinity constant is 0.688 nM.

Jagged1 Recombinant antibody, PBS Only

Jagged1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84694-1-PBS

产品说明书

CloneNo. 241412F1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

JAG1, Protein jagged-1, HJ1, CD339, 241412F1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84694-1-PBS targets Jagged1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 jagged 1 (Alagille syndrome)
别名 JAG1, Protein jagged-1, HJ1, CD339, 241412F1
计算分子量 1218 aa, 134 kDa
观测分子量150 kDa
GenBank蛋白编号BC098393
基因名称 Jagged1
Gene ID (NCBI) 182
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP78504
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).